![]() ![]() As these protocols were investigated, it became apparent to the committee that the full body of knowledge available to the wartime scientists, especially information relevant to the long-term health outcomes of exposure to these agents, was not applied in the conduct of the human experimentation. These estimates were intended to put into context the concentrations of vesicant used in animal and other types of experiments, which the committee was also charged to survey. ![]() This committee also investigated as many protocols and supporting military documents as it could obtain for use in estimating the possible exposure levels experienced by the men who participated in the mustard and Lewisite tests. The major focus of this chapter, however, is to describe the research programs and protocols relating to mustard agents and Lewisite, initiated just prior to World War II (WWII) and continued throughout the war. This is followed by a description of the organization of chemical warfare research during World War I (WWI) and the postwar period of 1919 to 1940, including the development of Lewisite and nitrogen mustard. ![]() This chapter begins with an introduction that briefly describes sulfur mustard and Lewisite and their effects, accompanied by an overview of their development. ![]()
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